Ultra-Sensitive Gene Methylation Amplification Technology (USGMAT)
The USGMAT is a proprietary technology that we used to develop Methylplus™ products. The USGMAT can quantitatively detect methylation alterations in the promotor regions in a real time, multiplex format. Compared to the current quantitative MS-PCR or other methylation-based gene amplification methods, USGMAT is much more rapid, simple, inexpensive and accurate in the quantification of methylated change and only needs extremely tiny amounts of starting DNA. Thus USGMAT can allow both high sensitivity and specificity to be achieved in detection of early-stage cancer and prediction of cancer therapy response.